The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

The San Francisco 49ers are teetering on the brink of potential disaster on the injury front as they prepare for their Week 11 showdown against the Seattle Seahawks. Thursday’s practice participation ...

San Francisco 49ers George Kittle lost a bet as he was seen wearing UCLA gear while speaking to reporters on Thursday. Kittle ...

George Kittle just keeps getting better. He's 31, which means he should be on the downside of his career, but he's not. He's ...

Brock Purdy takes a 5-0 record against the Seahawks into Sunday’s game, while counterpart Geno Smith looks for his first win ...

A nearly forgotten third-string QB is the man 49ers fans really need to thank for Brock Purdy and George Kittle.

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.

The San Francisco 49ers (5-4) have 11 players on the injury report, including George Kittle, ahead of their matchup against ...

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

San Francisco 49ers quarterback Brock Purdy was announced as NFL Slimetime's "Nickelodeon Valuable Player" for Week 10.

The San Francisco 49ers kicked off their Week 11 practices with a handful off injury issues keeping players from practicing ...