The Indianapolis Colts will need to navigate Week 5 against the Jacksonville Jaguars without their starting quarterback Anthony Richardson. Richardson has been ruled out for this contest and backup quarterback Joe Flacco will start the game.

The Indianapolis Colts have a long injury list as they try to keep the Jacksonville Jaguars winless in NFL Week 5.

We’re officially through four weeks of the NFL season, and the injuries continue to pile up. Colts quarterback Anthony Richardson left his team's game against the Steelers with an oblique strain. His teammate Jonathan Taylor exited earlier with an ankle injury. Packers receiver Christian Watson also suffered a high ankle sprain against the Vikings.